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Post by batman on Sept 7, 2018 5:47:12 GMT -6
I need a high fence. Would sure make aging easy. 😎 In theory as soon as Simpson and Haley finish their work we will have a pretty good grip on genetic markers and how old those deer need to be +/- to contract CWD. If you know your deer genotype you can target them before that age. Voila. No CWD inside the fence. In theory. |
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Post by wiscwhip on Sept 7, 2018 6:04:52 GMT -6
I need a high fence. Would sure make aging easy. 😎 In theory as soon as Simpson and Haley finish their work we will have a pretty good grip on genetic markers and how old those deer need to be +/- to contract CWD. If you know your deer genotype you can target them before that age. Voila. No CWD inside the fence. In theory. So when you say, "how old those deer need to be +/- to contract CWD", are you insinuating that they can not be born with CWD to a mother who has tested positive before or during pregnancy? |
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Post by batman on Sept 7, 2018 6:13:00 GMT -6
In theory as soon as Simpson and Haley finish their work we will have a pretty good grip on genetic markers and how old those deer need to be +/- to contract CWD. If you know your deer genotype you can target them before that age. Voila. No CWD inside the fence. In theory. So when you say, "how old those deer need to be +/- to contract CWD", are you insinuating that they can not be born with CWD to a mother who has tested positive before or during pregnancy? I don't know. It was reason the prions would pass from mother to fawn, but if you kill a deer below the age it will contract CWD it cant contract CWD. In theory. And some genotypes have been shown much more resistant to CWD. It would be interesting to know if a does threw twins and one was a G and one was a K if they would both be passed cwd and at what ages. |
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Post by wiscwhip on Sept 7, 2018 6:56:26 GMT -6
I am having a hard time grasping what you are saying. If the mother has it and her blood flows through the fawn, it stands to reason that fawn would have prions in it's system, whether they show signs of CWD or not, they are surely a "carrier", no?
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Post by batman on Sept 7, 2018 15:20:46 GMT -6
I am having a hard time grasping what you are saying. If the mother has it and her blood flows through the fawn, it stands to reason that fawn would have prions in it's system, whether they show signs of CWD or not, they are surely a "carrier", no? There is debate that prions are not shed until a certain stage of infection. Apparently there are 4 different stages of obex infection and prions not shed until cant remember which one. But it is an area that needs research. CWD is a frequency dependent disease meaning certain amount of causative agent is needed to infect a deer. Some genotypes have a higher threshold. Inject concentrated amounts into the brain (highly unnatural) the frequency is off the charts and infection rates very high. |
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Post by wiscwhip on Sept 7, 2018 15:43:27 GMT -6
I am having a hard time grasping what you are saying. If the mother has it and her blood flows through the fawn, it stands to reason that fawn would have prions in it's system, whether they show signs of CWD or not, they are surely a "carrier", no? There is debate that prions are not shed until a certain stage of infection. Apparently there are 4 different stages of obex infection and prions not shed until cant remember which one. But it is an area that needs research. CWD is a frequency dependent disease meaning certain amount of causative agent is needed to infect a deer. Some genotypes have a higher threshold. Inject concentrated amounts into the brain (highly unnatural) the frequency is off the charts and infection rates very high.This ^^^ is why much research on transmission vectors is suspect to date, as injection is the only real way to get "quick" specimens for studies. That said, it is an unnatural vector and could quite possibly skew any results one might achieve or it could negate treatments that would work on deer in the early stages of the disease that have far lower concentrations of the infecting agent in their systems. |
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